In addition to her commercial appearances, she was a series regular on the Yahoo! Screen science fiction comedy Other Space (2015) and had a recurring role on the NBC drama This Is Us (2016–2017).
She came to prominence for her appearances in AT&T television commercials as saleswoman Lily Adams from 2013 to 2016 and since 2020. The daughter of Jewish refugees, she began her career as a child actress shortly after immigrating to the United States. Milana Aleksandrovna Vayntrub (/ˈvaɪntruːb/ VYN-troob, phonetic transliteration of Weintrub) Uzbek Cyrillic: Милана Александровна Вайнтруб born March 8, 1987) is a Soviet-born American actress, comedian and activist.